- Scottish Rite Center
- Scotts Auto Express
- Scottsdale Convention and Visitors Bureau
- Scottsdale Healthcare Thompson Peak Hospital
- Scottsdale Healthcare-Osborn
- Scottsdale Insurance
- Scottts Bluff Dialysis Center
- Screven County Hospital
- Scripps Green Hospital
- Scripps Green Hospital Center For Organ and Cell Transplantation
- Scripps Health
- Scripps Memorial Hospital Encinitas
- Scripps Memorial Hospital La Jolla
- Scripps Mercy Hospital
- Scripps Mercy Hospital Chula Vista
- Scriptsave
- SDX Logistics
- Sea Crest Oceanfront Resort and Conference Center
- Sea Ranch Lodge, CA
- Sea Services
- Sea Turtle Inn, Jacksonville
- Seabrook Wallcoverings
- Sealeze A Unit of Jason Inc.
- Search to Involve Pilipino Americans
- Search Wide
- Sears Contract Sales
- Sears Holdings Co.
- Sears Logistics Services
- Sears Roebuck and Co.
- Sears Roebuck and Co., Inc.
- Seashore Gardens
- Seaside Inn, Sanibel Island
- Seasongood and Mayer, LLC
- Seasons Center for Behavioral Health
- Seattle University, School of Nursing
- Seattle's Convention and Visitors Bureau
- Sebastian River Medical Center
- Second Wind Lung Transplant Association, Inc.
- Secure Care Products, Inc.
- Securitan
- Security Business Archives, Inc.
- Security Consultants Group, Inc.
- Security Corporation
- Security Financial Corporation
- Security Forces, Inc.
- Security National Bank
- Security Savings Bank
- Sedgwick County Osteopathic Medical Association
- SEI
- Seif and Associates, Inc.